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mouse IL16 shRNA silencing Adenovirus

Name 
Ad-m-IL16-shRNA
Cat No 
shADV-262107
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Il16.

shADV-262107
Ad-m-IL16-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Il16 (interleukin 16). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
mKIAA4048
Description (Vector)
Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4|Function: Isoform 1 may act as a scaffolding protein that anchors ion channels in the membrane|Function: Isoform 3 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.
Gene ID
16170
Gene Name (Vector)
interleukin 16
Gene Symbol
Il16
ORF Size (aa)
3969
ORF Size (bp)
3969 bp
RefSeq ID
NM_010551
RefSeq Synonyms
NM_010551, BC058709,
Species
mouse
UniGene ID
Mm.10137

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.