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human IL16 shRNA silencing AAV

Name 
AAV-h-IL16-shRNA
Cat No 
shAAV-212056
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human IL16.

shAAV-212056
AAV-h-IL16-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human IL16 (interleukin 16). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
LCF; NIL16; prIL-16; PRIL16
Description (Vector)
IL16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants.
Gene ID
3603
Gene Name (Vector)
interleukin 16
Gene Symbol
IL16
HGNC ID
HGNC:5980
ORF Size (aa)
3996
ORF Size (bp)
3996 bp
RefSeq ID
NM_004513
RefSeq Synonyms
NM_172217, NM_004513, NM_001172128, BC136660, BC040272,
Species
human
UniGene ID
Hs.459095

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.