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mouse IBTK shRNA silencing Adenovirus

Name 
Ad-m-IBTK-shRNA
Cat No 
shADV-261821
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Ibtk.

shADV-261821
Ad-m-IBTK-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Ibtk (inhibitor of Bruton agammaglobulinemia tyrosine kinase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
5430411K16Rik; AA409502; BTKI; mKIAA1417
Description (Vector)
Acts as an inhibitor of BTK tyrosine kinase activity, thereby playing a role in B-cell development. Down-regulates BTK kinase activity, leading to interference with BTK-mediated calcium mobilization and NF-kappa-B-driven transcription.
Gene ID
108837
Gene Name (Vector)
inhibitor of Bruton agammaglobulinemia tyrosine kinase
Gene Symbol
Ibtk
ORF Size (aa)
4059
ORF Size (bp)
4059 bp
RefSeq ID
NM_001081282
RefSeq Synonyms
NM_001081282, BC137798,
Species
mouse
UniGene ID
Mm.22315

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.