mouse HSPA1B shRNA silencing Adenovirus

Name 
Ad-m-HSPA1B-shRNA
Cat No 
shADV-261734
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Hspa1b.

shADV-261734
Ad-m-HSPA1B-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Hspa1b (heat shock protein 1B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
hsp68; Hsp70; Hsp70-1; Hsp70.1
Description (Vector)
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.
Gene ID
15511
Gene Name (Vector)
heat shock protein 1B
Gene Symbol
Hspa1b
ORF Size (aa)
1926
ORF Size (bp)
1926 bp
RefSeq ID
NM_010478
RefSeq Synonyms
NM_010478, BC157921, BC152841, BC151109, BC151107,
Species
mouse
UniGene ID
Mm.372314

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.