mouse HMGN3 shRNA silencing Adenovirus

Name 
Ad-m-HMGN3-shRNA
Cat No 
shADV-261481
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Hmgn3.

shADV-261481
Ad-m-HMGN3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Hmgn3 (high mobility group nucleosomal binding domain 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
1110002A15Rik; 6330514M13Rik; BB071015; TRIP7
Description (Vector)
Binds to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. Affects both insulin and glucagon levels and modulates the expression of pancreatic genes involved in insulin secretion. Regulates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors. Regulates the expression of SLC6A9, a glycine transporter which regulates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. May play a role in ocular development and astrocyte function (By similarity).
Gene ID
94353
Gene Name (Vector)
high mobility group nucleosomal binding domain 3
Gene Symbol
Hmgn3
ORF Size (aa)
288
ORF Size (bp)
288 bp
RefSeq ID
NM_175074
RefSeq Synonyms
NM_175074, NM_026122, BC005693,
Species
mouse
UniGene ID
Mm.244426

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.