mouse GRK1 shRNA silencing Adenovirus

Name 
Ad-m-GRK1-shRNA
Cat No 
shADV-260780
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Grk1.

shADV-260780
Ad-m-GRK1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Grk1 (G protein-coupled receptor kinase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Gprk1; Rhok; Rk
Description (Vector)
Retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin (RHO), the G protein- coupled receptor that initiates the phototransduction cascade. This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination.
Gene ID
24013
Gene Name (Vector)
G protein-coupled receptor kinase 1
Gene Symbol
Grk1
ORF Size (aa)
1695
ORF Size (bp)
1695 bp
RefSeq ID
NM_011881
RefSeq Synonyms
NM_011881, BC096611,
Species
mouse
UniGene ID
Mm.257501

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.