mouse GRIA3 shRNA silencing Adenovirus

Name 
Ad-m-GRIA3-shRNA
Cat No 
shADV-260751
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Gria3.

shADV-260751
Ad-m-GRIA3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Gria3 (glutamate receptor, ionotropic, AMPA3 (alpha 3)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
2900064I19Rik; GluA3; Glur-3; GluR-C; GluR-K3; Glur3; Gluralpha3
Description (Vector)
Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Gene ID
53623
Gene Name (Vector)
glutamate receptor, ionotropic, AMPA3 (alpha 3)
Gene Symbol
Gria3
ORF Size (aa)
2667
ORF Size (bp)
2667 bp
RefSeq ID
NM_016886
RefSeq Synonyms
NM_016886, NM_001290451, NM_001281929, BC129856, BC129855, BC086678,
Species
mouse
UniGene ID
Mm.327681

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.