mouse GRB14 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Grb14.
shADV-260735
Ad-m-GRB14-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Grb14 (growth factor receptor bound protein 14). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI505286
Description (Vector)
Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.
Gene ID
50915
Gene Name (Vector)
growth factor receptor bound protein 14
Gene Symbol
Grb14
ORF Size (aa)
1617
ORF Size (bp)
1617 bp
RefSeq ID
NM_016719
RefSeq Synonyms
NM_016719, BC145913, BC138581,
Species
mouse
UniGene ID
Mm.214554
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.