mouse GPR120 shRNA silencing Adenovirus

Name 
Ad-m-GPR120-shRNA
Cat No 
shADV-260561
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Ffar4.

shADV-260561
Ad-m-GPR120-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Ffar4 (free fatty acid receptor 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AI552415; Gpr120; Gpr129; GT01; KPG_013; O3far1; Pgr4
Description (Vector)
Receptor for medium and long-chain free fatty acid (FAA). Signals via a G(q)/G(11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects particularly in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1 dependent effect but independent of G(q)/G(11)-coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage-induced tissue inflammation. May mediates the taste of fatty acids (By similarity).
Gene ID
107221
Gene Name (Vector)
free fatty acid receptor 4
Gene Symbol
Ffar4
ORF Size (aa)
1086
ORF Size (bp)
1086 bp
RefSeq ID
NM_181748
RefSeq Synonyms
NM_181748, BC053698,
Species
mouse
UniGene ID
Mm.35288

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.