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human LHCGR shRNA silencing AAV

Name 
AAV-h-LHCGR-shRNA
Cat No 
shAAV-213888
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human LHCGR.

shAAV-213888
AAV-h-LHCGR-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human LHCGR (luteinizing hormone/choriogonadotropin receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HHG; LCGR; LGR2; LH/CG-R; LH/CGR; LHR; LHRHR; LSH-R; ULG5
Description (Vector)
LHCGR encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia.
Gene ID
3973
Gene Name (Vector)
luteinizing hormone/choriogonadotropin receptor
Gene Symbol
LHCGR
HGNC ID
HGNC:6585
ORF Size (aa)
2097
ORF Size (bp)
2097 bp
RefSeq ID
NM_000233
RefSeq Synonyms
NM_000233, BC157028, BC156303,
Species
human
UniGene ID
Hs.468490

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.