human MKS1 Over-expression AAV

Name
AAV-h-MKS1

Cat No
AAV-215507

Availability
4-5 weeks

This is an AAV expressing Human MKS1.

AAV-215507

AAV-h-MKS1

Ready-to-use AAV expressing Human MKS1 (Meckel syndrome, type 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

BBS13; JBTS28; MES; MKS; POC12

Description (Vector)

MKS1 localizes to the basal body and is required for formation of the primary cilium in ciliated epithelial cells. Mutations in this gene result in Meckel syndrome type 1 and in Bardet-Biedl syndrome type 13. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID

54903

Gene Name (Vector)

Meckel syndrome, type 1

Gene Symbol

MKS1

HGNC ID

HGNC:7121

ORF Size (aa)

1134

ORF Size (bp)

1134 bp

RefSeq ID

NM_017777

RefSeq Synonyms

NM_017777, NM_001330397, NM_001321269, NM_001321268, NM_001165927, BC010061,

Species

human

UniGene ID

Hs.408843

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.