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mouse GPM6A shRNA silencing Adenovirus

Name 
Ad-m-GPM6A-shRNA
Cat No 
shADV-260527
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Gpm6a.

shADV-260527
Ad-m-GPM6A-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Gpm6a (glycoprotein m6a). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Gpm6; M6A
Description (Vector)
Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
Gene ID
234267
Gene Name (Vector)
glycoprotein m6a
Gene Symbol
Gpm6a
ORF Size (aa)
804
ORF Size (bp)
804 bp
RefSeq ID
NM_153581
RefSeq Synonyms
NM_153581, NM_001253756, NM_001253754, BC043130, BC033394, BC033357, BC029711, BC029683, BC024759, BC023461,
Species
mouse
UniGene ID
Mm.241700

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.