human MIS12 Over-expression AAV

Name 
AAV-h-MIS12
Cat No 
AAV-215487
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human MIS12.

AAV-215487
AAV-h-MIS12

Ready-to-use AAV expressing Human MIS12 (MIS12, kinetochore complex component). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2510025F08Rik; hMis12; homolog of yeast Mis12; KNTC2AP; MIS12 homolog; MIS12, MIND kinetochore complex component, homolog; MTW1; protein MIS12 homolog
Description (eCommerce)
MIS12 is an inner kinetochore protein found in a complex with Dsn1, Nnf1, and Nsl1 that functions in kinetochore assembly. This MIS12 complex has been demonstrated to be required for proper chromosome alignment and cell cycle progression.
Gene ID
79003
Gene Name (eCommerce)
MIS12, kinetochore complex component
Gene Name (Vector)
MIS12, kinetochore complex component
Gene Symbol
MIS12
HGNC ID
HGNC:24967
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
618
ORF Size (bp)
618 bp
Protein Name (eCommerce)
Protein MIS12 homolog
RefSeq ID
NM_024039
RefSeq Synonyms
NM_024039, NM_001258220, NM_001258219, NM_001258218, NM_001258217, BC000229,
Research Areas
Cell Cycle,Cell Division
Research Areas (Faceted)
cell_biology,cell_cycle,genetics
Species
human
Target Sentence
MIS12 is an inner kinetochore protein found in a complex with Dsn1, Nnf1, and Nsl1 that functions in kinetochore assembly. This MIS12 complex has been demonstrated to be required for proper chromosome alignment and cell cycle progression.
UniGene ID
Hs.267194
UniProt ID (eCommerce)
Q9H081

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.