mouse GADD45A shRNA silencing Adenovirus

Name 
Ad-m-GADD45A-shRNA
Cat No 
shADV-259827
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Gadd45a.

shADV-259827
Ad-m-GADD45A-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Gadd45a (growth arrest and DNA-damage-inducible 45 alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AA545191; Ddit1; GADD45
Description (Vector)
In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity). Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase.
Gene ID
13197
Gene Name (Vector)
growth arrest and DNA-damage-inducible 45 alpha
Gene Symbol
Gadd45a
ORF Size (aa)
498
RefSeq ID
NM_007836
RefSeq Synonyms
NM_007836, BC011141,
Species
mouse
UniGene ID
Mm.389750

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.