mouse FLNA shRNA silencing Adenovirus

Name 
Ad-m-FLNA-shRNA
Cat No 
shADV-259470
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Flna.

shADV-259470
Ad-m-FLNA-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Flna (filamin, alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ABP-280; Dilp2; F730004A14Rik; filamin-1; Fln1; GENA 379
Description (Vector)
Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis.
Gene ID
192176
Gene Name (Vector)
filamin, alpha
Gene Symbol
Flna
ORF Size (aa)
7920
ORF Size (bp)
7920 bp
RefSeq ID
NM_010227
RefSeq Synonyms
NM_010227, NM_001290421, BC151024,
Species
mouse
UniGene ID
Mm.295533

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.