mouse FBXO11 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Fbxo11.
shADV-259221
Ad-m-FBXO11-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Fbxo11 (F-box protein 11). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C80048; Jf
Description (Vector)
Substrate recognition component of the a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Binds to and neddylates phosphorylated p53/TP53, inhibiting its transcriptional activity. SCF(FBXO11) does not seem to direct ubiquitination of TP53.
Gene ID
225055
Gene Name (Vector)
F-box protein 11
Gene Symbol
Fbxo11
ORF Size (aa)
2529
ORF Size (bp)
2529 bp
RefSeq ID
NM_001081034
RefSeq Synonyms
NM_001081034, BC128479, BC117885, BC117884,
Species
mouse
UniGene ID
Mm.386857
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.