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mouse ESPL1 shRNA silencing Adenovirus

Name 
Ad-m-ESPL1-shRNA
Cat No 
shADV-258712
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Espl1.

shADV-258712
Ad-m-ESPL1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Espl1 (extra spindle pole bodies 1, separase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AL024103; AU045071; Cerp; ESP1; PRCE; SSE
Description (Vector)
Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms.
Gene ID
105988
Gene Name (Vector)
extra spindle pole bodies 1, separase
Gene Symbol
Espl1
ORF Size (aa)
6357
ORF Size (bp)
6357 bp
RefSeq ID
NM_001014976
RefSeq Synonyms
NM_001014976, BC145846, BC145844, BC082603,
Species
mouse
UniGene ID
Mm.288324

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.