mouse DAB2IP shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Dab2ip.
shADV-256781
Ad-m-DAB2IP-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Dab2ip (disabled 2 interacting protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2310011D08Rik; AI480459; Aip1; mKIAA1743
Description (Vector)
Functions as a Ras GTPase-activating protein (By similarity). Through its interaction with MAP3K5 disrupts the association of MAP3K5 with the inhibitory 14-3-3 complex. Mediates TNF/TRAF2-induced MAP3K5-JNK activation, while it inhibits CHUK-NF-kappa-B signaling. May act as a tumor suppressor gene.
Gene ID
69601
Gene Name (Vector)
disabled 2 interacting protein
Gene Symbol
Dab2ip
ORF Size (aa)
3198
ORF Size (bp)
3198 bp
RefSeq ID
NM_001114125
RefSeq Synonyms
NM_001290641, NM_001290640, NM_001290639, NM_001290637, NM_001114125, NM_001114124, NM_001001602, BC118530,
Species
mouse
UniGene ID
Mm.29629
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.