human MCCC2 Over-expression AAV

Name 
AAV-h-MCCC2
Cat No 
AAV-215159
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human MCCC2.

AAV-215159
AAV-h-MCCC2

Ready-to-use AAV expressing Human MCCC2 (methylcrotonoyl-CoA carboxylase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
MCCB
Description (Vector)
MCCC2 encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism.
Gene ID
64087
Gene Name (Vector)
methylcrotonoyl-CoA carboxylase 2
Gene Symbol
MCCC2
HGNC ID
HGNC:6937
ORF Size (aa)
1692
ORF Size (bp)
1692 bp
RefSeq ID
NM_022132
RefSeq Synonyms
NM_022132, BC065027, BC014897,
Species
human
UniGene ID
Hs.604789

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.