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mouse CIRBP shRNA silencing Adenovirus

Name 
Ad-m-CIRBP-shRNA
Cat No 
shADV-255509
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Cirbp.

shADV-255509
Ad-m-CIRBP-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Cirbp (cold inducible RNA binding protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Cirp; R74941
Description (Vector)
Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.
Gene ID
12696
Gene Name (Vector)
cold inducible RNA binding protein
Gene Symbol
Cirbp
ORF Size (aa)
519
ORF Size (bp)
519 bp
RefSeq ID
NM_007705
RefSeq Synonyms
NM_007705, BC075699,
Species
mouse
UniGene ID
Mm.17898

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.