mouse CHTF18 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Chtf18.
shADV-255488
Ad-m-CHTF18-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Chtf18 (CTF18, chromosome transmission fidelity factor 18). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
6030457M03Rik; Chl12; CTF18
Description (Vector)
Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated by the presence of primed DNA, replication protein A (RPA) and by proliferating cell nuclear antigen (PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loading of PCNA onto primed and gapped DNA. It also interacts with and stimulates DNA polymerase POLH.
Gene ID
214901
Gene Name (Vector)
CTF18, chromosome transmission fidelity factor 18
Gene Symbol
Chtf18
ORF Size (aa)
2910
ORF Size (bp)
2910 bp
RefSeq ID
NM_145409
RefSeq Synonyms
NM_145409, BC024142,
Species
mouse
UniGene ID
Mm.102540
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.