human CHRNB2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CHRNB2.
shAAV-205222
AAV-h-CHRNB2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CHRNB2 (cholinergic receptor nicotinic beta 2 subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EFNL3; nAChRB2
Description (Vector)
Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy.
Gene ID
1141
Gene Name (Vector)
cholinergic receptor nicotinic beta 2 subunit
Gene Symbol
CHRNB2
HGNC ID
HGNC:1962
ORF Size (aa)
1509
ORF Size (bp)
1509 bp
RefSeq ID
NM_000748
RefSeq Synonyms
NM_000748, BC075041, BC075040,
Species
human
UniGene ID
Hs.2306
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.