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mouse CCR4 shRNA silencing Adenovirus

Name 
Ad-m-CCR4-shRNA
Cat No 
shADV-254903
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Ccr4.

shADV-254903
Ad-m-CCR4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Ccr4 (chemokine (C-C motif) receptor 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
C-C CKR-4; CHEMR1; Cmkbr4; LESTR; Sdf1r
Description (Vector)
High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.
Gene ID
12773
Gene Name (Vector)
chemokine (C-C motif) receptor 4
Gene Symbol
Ccr4
ORF Size (aa)
1083
ORF Size (bp)
1083 bp
RefSeq ID
NM_009916
RefSeq Synonyms
NM_009916, BC119171, BC117041,
Species
mouse
UniGene ID
Mm.1337

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.