mouse BLOC1S1 shRNA silencing Adenovirus

Name 
Ad-m-BLOC1S1-shRNA
Cat No 
shADV-254001
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Bloc1s1.

shADV-254001
Ad-m-BLOC1S1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Bloc1s1 (biogenesis of lysosomal organelles complex-1, subunit 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AI839753; BLOS1; Gcn5l1
Description (Vector)
BLOC1S1 may negatively regulate aerobic respiration through mitochondrial protein lysine-acetylation. May counteract the action of the deacetylase SIRT3 by acetylating and regulating proteins of the mitochondrial respiratory chain including ATP5A1 AND NDUFA9. May also be involved in the biogenesis of specialized organelles of the endosomal-lysosomal system.
Gene ID
14533
Gene Name (Vector)
biogenesis of lysosomal organelles complex-1, subunit 1
Gene Symbol
Bloc1s1
ORF Size (aa)
378
ORF Size (bp)
378 bp
RefSeq ID
NM_015740
RefSeq Synonyms
NM_015740, BC034662,
Species
mouse
UniGene ID
Mm.30118

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.