mouse BCOR shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Bcor.
shADV-253918
Ad-m-BCOR-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Bcor (BCL6 interacting corepressor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2900008C10Rik; 5830466J11Rik; 8430401K06Rik; BcorR; D930024N20Rik; mKIAA1575
Description (Vector)
Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 'Lys-4' (H3K4me3) and 'Lys-36' (H3K36me2).
Gene ID
71458
Gene Name (Vector)
BCL6 interacting corepressor
Gene Symbol
Bcor
ORF Size (aa)
5178
ORF Size (bp)
5178 bp
RefSeq ID
NM_029510
RefSeq Synonyms
NM_175046, NM_175045, NM_175044, NM_029510, NM_001168321, BC058656,
Species
mouse
UniGene ID
Mm.196328
Recently Viewed Products
Ad-CMV-Luc
Cat No: 1000
Ad-CMV-Akt1 (Myr)
Cat No: 1020
Ad-CMV-Akt1 (dn)
Cat No: 1021
Ad-CMV-Akt1 (wt)
Cat No: 1022
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.