mouse BCL10 shRNA silencing Adenovirus

Name
Ad-m-BCL10-shRNA

Cat No
shADV-253873

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Bcl10.

shADV-253873

Ad-m-BCL10-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Bcl10 (B cell leukemia/lymphoma 10). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

AI132454; BCL-10; C81403; CARMEN; cE10; CIPER; CLAP; ME10

Description (Vector)

Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1.

Gene ID

12042

Gene Name (Vector)

B cell leukemia/lymphoma 10

Gene Symbol

Bcl10

ORF Size (aa)

702

RefSeq ID

NM_009740

RefSeq Synonyms

NM_009740, BC172009, BC172007, BC024379,

Species

mouse

UniGene ID

Mm.239141

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.