mouse ATF7 shRNA silencing Adenovirus

Name 
Ad-m-ATF7-shRNA
Cat No 
shADV-253214
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse ATF7.

shADV-253214
Ad-m-ATF7-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse ATF7 (activating transcription factor 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
1110012F10Rik; 9430065F09Rik; AI549878; C130020M04Rik; MGC31554;
Description (Vector)
Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family|Function: Isoform 4/ATF-A0 acts as a dominant repressor of the E-selectin/NF-ELAM1/delta-A promoter|Function: Isoform 5/ATF-4 acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation.
Gene ID
223922
Gene Name (Vector)
activating transcription factor 7
Gene Symbol
ATF7
ORF Size (aa)
1242
ORF Size (bp)
1242 bp
RefSeq ID
NM_146065
RefSeq Synonyms
NM_146065, NM_001310070, NM_001310067, NM_001310066, BC026483,
Species
mouse
UniGene ID
Mm.475149

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.