mouse ASXL2 shRNA silencing Adenovirus

Name 
Ad-m-ASXL2-shRNA
Cat No 
shADV-253185
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Asxl2.

shADV-253185
Ad-m-ASXL2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Asxl2 (additional sex combs like 2 (Drosophila)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
4930556B16Rik; mKIAA1685
Description (Vector)
Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility (By similarity). Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as peroxisome proliferator-activated receptor gamma (PPARG). Acts as coactivator for PPARG and enhances its adipocyte differentiation-inducing activity; the function seems to involve differential recruitment of acetylated and methylated histone H3.
Gene ID
75302
Gene Name (Vector)
additional sex combs like 2 (Drosophila)
Gene Symbol
Asxl2
ORF Size (aa)
4113
ORF Size (bp)
4113 bp
RefSeq ID
NM_172421
RefSeq Synonyms
NM_172421, NM_001270988, BC166033, BC141140,
Species
mouse
UniGene ID
Mm.120475

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.