mouse ASNA1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Asna1.
shADV-253156
Ad-m-ASNA1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Asna1 (arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1810048H22Rik; ArsA
Description (Vector)
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting (By similarity). May be involved in insulin signaling.
Gene ID
56495
Gene Name (Vector)
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
Gene Symbol
Asna1
ORF Size (aa)
1047
ORF Size (bp)
1047 bp
RefSeq ID
NM_019652
RefSeq Synonyms
NM_019652, BC083335, BC018430, BC016453,
Species
mouse
UniGene ID
Mm.41475
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.