mouse AADAC shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Aadac.
shADV-251727
Ad-m-AADAC-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Aadac (arylacetamide deacetylase (esterase)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
5033417E09Rik; Aada; AI265437
Description (Vector)
Arylacetamide deacetylation is an important enzyme activity in the metabolic activation of arylamine substrates to ultimate carcinogens. Displays major serine hydrolase activity in liver microsomes. Hydrolyzes also flutamide, which is an antiandrogen drug used for the treatment of prostate cancer that occasionaly causes severe hepatotoxicity. Displays cellular triglyceride lipase activity in liver. Increases intracellular fatty acids derived from hydrolysis of newly formed triglyceride stores.
Gene ID
67758
Gene Name (Vector)
arylacetamide deacetylase (esterase)
Gene Symbol
Aadac
ORF Size (aa)
1197
ORF Size (bp)
1197 bp
RefSeq ID
NM_023383
RefSeq Synonyms
NM_023383, BC054823, BC019999,
Species
mouse
UniGene ID
Mm.24547
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.