human DEAF1 shRNA silencing Adenovirus

Name 
Ad-h-DEAF1-shRNA
Cat No 
shADV-231176
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human DEAF1.

shADV-231176
Ad-h-DEAF1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human DEAF1 (DEAF1, transcription factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
deformed epidermal autoregulatory factor 1 homolog; MRD24; nuclear DEAF-1-related transcriptional regulator; NUDR; SPN; suppressin; zinc finger MYND domain-containing protein 5; ZMYND5
Description (eCommerce)
Deformed epidermal autoregulatory factor 1 homolog (DEAF1) is a transcription factor that binds to sequences with multiple copies of 5'-TTC[CG]G-3' present in its own promoter and that of the HNRPA2B1 gene and also binds to the retinoic acid response element (RARE) 5'-AGGGTTCACCGAAAGTTCA-3'. DEAF1 regulates epithelial cell proliferation and side-branching in the mammary gland and also controls the expression of peripheral tissue antigens in pancreatic lymph nodes [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ O75398].
Gene ID
10522
Gene Name (eCommerce)
DEAF1 transcription factor
Gene Name (Vector)
DEAF1, transcription factor
Gene Symbol
DEAF1
HGNC ID
HGNC:14677
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1698
ORF Size (bp)
1698 bp
Protein Name (eCommerce)
Deformed epidermal autoregulatory factor 1 homolog
RefSeq ID
NM_021008
RefSeq Synonyms
NM_021008, NM_001293634, BC053322,
Research Areas
Neurobiology,Neurodevelopment,Neurogenesis,Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
cell_biology,developmental_biology,neurobiology,transcription_translation
Species
human
Target Sentence
Deformed epidermal autoregulatory factor 1 homolog (DEAF1) is a transcription factor that binds to sequences with multiple copies of 5'-TTC[CG]G-3' present in its own promoter and that of the HNRPA2B1 gene and also binds to the retinoic acid response element (RARE) 5'-AGGGTTCACCGAAAGTTCA-3'. DEAF1 regulates epithelial cell proliferation and side-branching in the mammary gland and also controls the expression of peripheral tissue antigens in pancreatic lymph nodes [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ O75398].
UniGene ID
Hs.243994
UniProt ID (eCommerce)
O75398

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.