human PPIG shRNA silencing Adenovirus

Name 
Ad-h-PPIG-shRNA
Cat No 
shADV-230881
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human PPIG.

shADV-230881
Ad-h-PPIG-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PPIG (peptidylprolyl isomerase G). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CARS-cyclophilin; CARS-Cyp; CASP10; Clk-associating RS-cyclophilin; cyclophilin G; CYP; peptidyl-prolyl cis-trans isomerase G; Peptidyl-prolyl isomerase G; peptidyl-prolyl isomerase G (cyclophilin G); PPIase G; rotamase G; SCAF10; SR-cyclophilin; SRCyp; SR-cyp; SR-related CTD-associated factor 10
Description (eCommerce)
SR cyclophilin (SRcyp) is also known as peptidyl-prolyl cis-trans isomerase G. Cyclophilins are peptidyl-prolyl isomerases (PPIases) that accelerate the folding of proteins by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. The function of cyclophilins is poorly understood, but their function has been linked to multiple cellular processes such as protein folding, trafficking, and chaperone activity. SRcyp is a member of the Moca family of nuclear cyclophilins and is phosphorylated in a cell cycle dependent manner. There is evidence that SRcyp may be involved in the regulation of gene expression and mRNA splicing.
Gene ID
9360
Gene Name (eCommerce)
peptidylprolyl isomerase G
Gene Name (Vector)
peptidylprolyl isomerase G
Gene Symbol
PPIG
HGNC ID
HGNC:14650
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2220
ORF Size (bp)
2220 bp
Protein Name (eCommerce)
Peptidyl-prolyl cis-trans isomerase G
RefSeq ID
NM_004792
RefSeq Synonyms
NM_004792, BC111693, BC001555,
Research Areas
Protein Folding,RNA Processing
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
SR cyclophilin (SRcyp) is also known as peptidyl-prolyl cis-trans isomerase G. Cyclophilins are peptidyl-prolyl isomerases (PPIases) that accelerate the folding of proteins by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. The function of cyclophilins is poorly understood, but their function has been linked to multiple cellular processes such as protein folding, trafficking, and chaperone activity. SRcyp is a member of the Moca family of nuclear cyclophilins and is phosphorylated in a cell cycle dependent manner. There is evidence that SRcyp may be involved in the regulation of gene expression and mRNA splicing.
UniGene ID
Hs.470544
UniProt ID (eCommerce)
Q13427

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.