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human GDF11 shRNA silencing Adenovirus

Name 
Ad-h-GDF11-shRNA
Cat No 
shADV-230502
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human GDF11.

shADV-230502
Ad-h-GDF11-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human GDF11 (growth differentiation factor 11). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BMP-11; BMP11
Description (Vector)
GDF11 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development.
Gene ID
10220
Gene Name (Vector)
growth differentiation factor 11
Gene Symbol
GDF11
HGNC ID
HGNC:4216
ORF Size (aa)
1221
ORF Size (bp)
1221 bp
RefSeq ID
NM_005811
RefSeq Synonyms
NM_005811, BC148591,
Species
human
UniGene ID
Hs.600883

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.