human ZFYVE20 shRNA silencing Adenovirus

Name
Ad-h-ZFYVE20-shRNA

Cat No
shADV-228237

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human RBSN.

shADV-228237

Ad-h-ZFYVE20-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RBSN (rabenosyn, RAB effector). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

No

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

110 kDa protein; FYVE finger-containing Rab5 effector protein rabenosyn-5; RAB effector RBSN; Rabenosyn-5; ZFYVE20; Zinc finger FYVE domain-containing protein 20; zinc finger, FYVE domain containing 20

Description (eCommerce)

ZFYVE20 belongs to the FYVE zinc finger family of proteins. It interacts with Ras-related proteins that regulate membrane trafficking. A missense mutation in the gene is associated with a defect in the early endocytic pathway [taken from NCBI Entrez Gene (Gene ID: 64145)].

Gene ID

64145

Gene Name (eCommerce)

rabenosyn, RAB effector

Gene Name (Vector)

rabenosyn, RAB effector

Gene Symbol

RBSN

HGNC ID

HGNC:20759

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

2355

ORF Size (bp)

2355 bp

Protein Name (eCommerce)

Rabenosyn-5

RefSeq ID

NM_022340

RefSeq Synonyms

NM_022340, NM_001302378, BC106940,

Research Areas

Immunology,Innate Immunity,Signal Transduction,Toll-like Receptor Signaling,Zinc-finger

Research Areas (Faceted)

signal_transduction,immunology,cell_biology

Species

human

Target Sentence

ZFYVE20 belongs to the FYVE zinc finger family of proteins. It interacts with Ras-related proteins that regulate membrane trafficking. A missense mutation in the gene is associated with a defect in the early endocytic pathway [taken from NCBI Entrez Gene (Gene ID: 64145)].

UniGene ID

Hs.706478

UniProt ID (eCommerce)

Q9H1K0

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.