human VAMP2 shRNA silencing Adenovirus

Name
Ad-h-VAMP2-shRNA

Cat No
shADV-227379

Availability
Immediate

This is an Adenovirus expressing shRNA for silencing of Human VAMP2.

shADV-227379

Ad-h-VAMP2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human VAMP2 (vesicle associated membrane protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

SYB2; VAMP-2

Description (Vector)

VAMP2 is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG.

Gene ID

6844

Gene Name (Vector)

vesicle associated membrane protein 2

Gene Symbol

VAMP2

HGNC ID

HGNC:12643

ORF Size (aa)

351

RefSeq ID

NM_014232

RefSeq Synonyms

NM_014232, NM_001330125, BC033870, BC019608, BC002737,

Species

human

UniGene ID

Hs.25348

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.