human UBE2D3 shRNA silencing Adenovirus

Name 
Ad-h-UBE2D3-shRNA
Cat No 
shADV-226999
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human UBE2D3.

shADV-226999
Ad-h-UBE2D3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human UBE2D3 (ubiquitin conjugating enzyme E2 D3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
E2(17)KB3; UBC4/5; UBCH5C
Description (Vector)
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.
Gene ID
7323
Gene Name (Vector)
ubiquitin conjugating enzyme E2 D3
Gene Symbol
UBE2D3
HGNC ID
HGNC:12476
ORF Size (aa)
444
RefSeq ID
NM_003340
RefSeq Synonyms
NM_181893, NM_181892, NM_181891, NM_181890, NM_181889, NM_181888, NM_181887, NM_181886, NM_003340, NM_001300795, BC066917, BC037894, BC003395,
Species
human
UniGene ID
Hs.518773

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.