human TUFM shRNA silencing Adenovirus

Name 
Ad-h-TUFM-shRNA
Cat No 
shADV-226858
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human TUFM.

shADV-226858
Ad-h-TUFM-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TUFM (Tu translation elongation factor, mitochondrial). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
COXPD4; EFTU; EF-Tu; EF-TuMT; elongation factor Tu, mitochondrial; epididymis secretory sperm binding protein; P43
Description (eCommerce)
TUFM/EF-Tu promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P49411].
Description (Vector)
TUFM encodes a protein which participates in protein translation in mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency resulting in lactic acidosis and fatal encephalopathy. A pseudogene has been identified on chromosome 17.
Gene ID
7284
Gene Name (eCommerce)
Tu translation elongation factor, mitochondrial
Gene Name (Vector)
Tu translation elongation factor, mitochondrial
Gene Symbol
TUFM
HGNC ID
HGNC:12420
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1368
ORF Size (bp)
1368 bp
Protein Name (eCommerce)
Elongation factor Tu, mitochondrial
RefSeq ID
NM_003321
RefSeq Synonyms
NM_003321, BC010041, BC001633,
Research Areas
Mitochondrion,Translational Control
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
TUFM/EF-Tu promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P49411].
UniGene ID
Hs.12084
UniProt ID (eCommerce)
P49411

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.