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human TRMT5 shRNA silencing Adenovirus

Name 
Ad-h-TRMT5-shRNA
Cat No 
shADV-226519
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human TRMT5.

shADV-226519
Ad-h-TRMT5-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TRMT5 (tRNA methyltransferase 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
COXPD26; KIAA1393; TRM5
Description (Vector)
tRNAs contain as many as 13 or 14 nucleotides that are modified posttranscriptionally by enzymes that are highly specific for particular nucleotides in the tRNA structure. TRMT5 methylates the N1 position of guanosine-37 (G37) in selected tRNAs using S-adenosyl methionine (Brule et al., 2004 (PubMed 15248782)).(supplied by OMIM, Mar 2008)
Gene ID
57570
Gene Name (Vector)
tRNA methyltransferase 5
Gene Symbol
TRMT5
HGNC ID
HGNC:23141
ORF Size (aa)
1530
ORF Size (bp)
1530 bp
RefSeq ID
NM_020810
RefSeq Synonyms
NM_020810, BC136607, BC136606, BC108284,
Species
human
UniGene ID
Hs.380159

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.