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human TRAF3 shRNA silencing Adenovirus

Name 
Ad-h-TRAF3-shRNA
Cat No 
shADV-226325
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human TRAF3.

shADV-226325
Ad-h-TRAF3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TRAF3 (TNF receptor associated factor 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1
Description (Vector)
TRAF3 is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported.
Gene ID
7187
Gene Name (Vector)
TNF receptor associated factor 3
Gene Symbol
TRAF3
HGNC ID
HGNC:12033
ORF Size (aa)
1707
ORF Size (bp)
1707 bp
RefSeq ID
NM_003300
RefSeq Synonyms
NM_145726, NM_145725, NM_003300, NM_001199427, BC075087, BC075086,
Species
human
UniGene ID
Hs.510528

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.