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human TPH1 shRNA silencing Adenovirus

Name 
Ad-h-TPH1-shRNA
Cat No 
shADV-226256
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human TPH1.

shADV-226256
Ad-h-TPH1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TPH1 (tryptophan hydroxylase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
TPRH; TRPH
Description (Vector)
TPH1 encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.
Gene ID
7166
Gene Name (Vector)
tryptophan hydroxylase 1
Gene Symbol
TPH1
HGNC ID
HGNC:12008
ORF Size (aa)
1335
ORF Size (bp)
1335 bp
RefSeq ID
NM_004179
RefSeq Synonyms
NM_004179, BC106739,
Species
human
UniGene ID
Hs.591999

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.