human TLR1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human TLR1.
shADV-225581
Ad-h-TLR1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human TLR1 (toll like receptor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD281; rsc786; TIL; TIL. LPRS5
Description (Vector)
TLR1 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene.
Gene ID
7096
Gene Name (Vector)
toll like receptor 1
Gene Symbol
TLR1
HGNC ID
HGNC:11847
ORF Size (aa)
2361
ORF Size (bp)
2361 bp
RefSeq ID
NM_003263
RefSeq Synonyms
NM_003263, BC109094, BC109093, BC089403,
Species
human
UniGene ID
Hs.654532
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.