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human THNSL2 shRNA silencing Adenovirus

Name 
Ad-h-THNSL2-shRNA
Cat No 
shADV-225447
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human THNSL2.

shADV-225447
Ad-h-THNSL2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human THNSL2 (threonine synthase like 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
SOFAT; THS2; TSH2
Description (Vector)
THNSL2 encodes a threonine synthase-like protein. A similar enzyme in mouse can catalyze the degradation of O-phospho-homoserine to a-ketobutyrate, phosphate, and ammonia. This protein also has phospho-lyase activity on both gamma and beta phosphorylated substrates. In mouse an alternatively spliced form of this protein has been shown to act as a cytokine and can induce the production of the inflammatory cytokine IL6 in osteoblasts. Alternate splicing results in multiple transcript variants.
Gene ID
55258
Gene Name (Vector)
threonine synthase like 2
Gene Symbol
THNSL2
HGNC ID
HGNC:25602
ORF Size (aa)
1218
RefSeq ID
NM_018271
RefSeq Synonyms
NM_018271, NM_001244678, NM_001244676, BC064423,
Species
human
UniGene ID
Hs.516179

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.