human THNSL2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human THNSL2.
shAAV-225447
AAV-h-THNSL2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human THNSL2 (threonine synthase like 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
SOFAT; THS2; TSH2
Description (Vector)
THNSL2 encodes a threonine synthase-like protein. A similar enzyme in mouse can catalyze the degradation of O-phospho-homoserine to a-ketobutyrate, phosphate, and ammonia. This protein also has phospho-lyase activity on both gamma and beta phosphorylated substrates. In mouse an alternatively spliced form of this protein has been shown to act as a cytokine and can induce the production of the inflammatory cytokine IL6 in osteoblasts. Alternate splicing results in multiple transcript variants.
Gene ID
55258
Gene Name (Vector)
threonine synthase like 2
Gene Symbol
THNSL2
HGNC ID
HGNC:25602
ORF Size (aa)
1218
RefSeq ID
NM_018271
RefSeq Synonyms
NM_018271, NM_001244678, NM_001244676, BC064423,
Species
human
UniGene ID
Hs.516179
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.