human TDRD7 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human TDRD7.
shADV-225273
Ad-h-TDRD7-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human TDRD7 (tudor domain containing 7). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CATC4; epididymis secretory sperm binding protein; PCTAIRE2-binding protein; PCTAIRE2BP; TRAP; tudor domain-containing protein 7; tudor repeat associator with PCTAIRE 2; Tudor repeat associator with PCTAIRE-2
Description (eCommerce)
The Tudor domain-containing protein 7 encoded by the gene TDRD7 belongs to the Tudor family of proteins. This protein contains conserved Tudor domains and LOTUS domains. It is a component of RNA granules, which function in RNA processing. Mutations in this gene have been associated with cataract formation in mouse and human [taken from NCBI Entrez Gene (Gene ID: 23424)].
Description (Vector)
TDRD7 encodes a component of cytoplasmic RNA granules which are involved in determining the fate of mRNAs. Mutation in this gene has been associated with pediatric cataracts. Mutation of the similar gene in mice has been associated with cataracts, glaucoma and a block in spermatogenesis.
Gene ID
23424
Gene Name (eCommerce)
tudor domain containing 7
Gene Name (Vector)
tudor domain containing 7
Gene Symbol
TDRD7
HGNC ID
HGNC:30831
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3297
ORF Size (bp)
3297 bp
Protein Name (eCommerce)
Tudor domain-containing protein 7
RefSeq ID
NM_014290
RefSeq Synonyms
NM_014290, NM_001302884, BC028694,
Research Areas
mRNA Binding,RNA Binding,Signal Transduction,Spermatogenesis
Research Areas (Faceted)
cell_biology,developmental_biology,genetics,signal_transduction,transcription_translation
Species
human
Target Sentence
The Tudor domain-containing protein 7 encoded by the gene TDRD7 belongs to the Tudor family of proteins. This protein contains conserved Tudor domains and LOTUS domains. It is a component of RNA granules, which function in RNA processing. Mutations in this gene have been associated with cataract formation in mouse and human [taken from NCBI Entrez Gene (Gene ID: 23424)].
UniGene ID
Hs.193842
UniProt ID (eCommerce)
Q8NHU6
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.