human STXBP5 shRNA silencing Adenovirus

Name 
Ad-h-STXBP5-shRNA
Cat No 
shADV-224676
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human STXBP5.

shADV-224676
Ad-h-STXBP5-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human STXBP5 (syntaxin binding protein 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
LGL3; LLGL3; Nbla04300
Description (Vector)
Syntaxin 1 is a component of the 7S and 20S SNARE complexes which are involved in docking and fusion of synaptic vesicles with the presynaptic plasma membrane. This gene encodes a syntaxin 1 binding protein. In rat, a similar protein dissociates syntaxin 1 from the Munc18/n-Sec1/rbSec1 complex to form a 10S complex, an intermediate which can be converted to the 7S SNARE complex. Thus this protein is thought to be involved in neurotransmitter release by stimulating SNARE complex formation. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID
134957
Gene Name (Vector)
syntaxin binding protein 5
Gene Symbol
STXBP5
HGNC ID
HGNC:19665
ORF Size (aa)
3348
ORF Size (bp)
3348 bp
RefSeq ID
NM_139244
RefSeq Synonyms
NM_139244, NM_001127715, BC113408, BC113382,
Species
human
UniGene ID
Hs.93534

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.