human STXBP5 shRNA silencing AAV

Name 
AAV-h-STXBP5-shRNA
Cat No 
shAAV-224676
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human STXBP5.

shAAV-224676
AAV-h-STXBP5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human STXBP5 (syntaxin binding protein 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
LGL3; LLGL3; Nbla04300
Description (Vector)
Syntaxin 1 is a component of the 7S and 20S SNARE complexes which are involved in docking and fusion of synaptic vesicles with the presynaptic plasma membrane. This gene encodes a syntaxin 1 binding protein. In rat, a similar protein dissociates syntaxin 1 from the Munc18/n-Sec1/rbSec1 complex to form a 10S complex, an intermediate which can be converted to the 7S SNARE complex. Thus this protein is thought to be involved in neurotransmitter release by stimulating SNARE complex formation. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID
134957
Gene Name (Vector)
syntaxin binding protein 5
Gene Symbol
STXBP5
HGNC ID
HGNC:19665
ORF Size (aa)
3348
ORF Size (bp)
3348 bp
RefSeq ID
NM_139244
RefSeq Synonyms
NM_139244, NM_001127715, BC113408, BC113382,
Species
human
UniGene ID
Hs.93534

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.