human SSH3 shRNA silencing Adenovirus

Name 
Ad-h-SSH3-shRNA
Cat No 
shADV-224393
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SSH3.

shADV-224393
Ad-h-SSH3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SSH3 (slingshot protein phosphatase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
hSSH-3L; protein phosphatase Slingshot homolog 3; slingshot 3; slingshot homolog 3; SSH3L; SSH-3L; SSH-like protein 3
Description (eCommerce)
SSH3, also known as slingshot-3, may function as a phosphatase that activates the actin severing protein, ADF/cofilin to indfluence actin dynamics. There are three members of the slingshot family, SSH1, SSH2, and SSH3.
Description (Vector)
The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 (PubMed 11832213)).(supplied by OMIM, Mar 2008)
Gene ID
54961
Gene Name (eCommerce)
slingshot protein phosphatase 3
Gene Name (Vector)
slingshot protein phosphatase 3
Gene Symbol
SSH3
HGNC ID
HGNC:30581
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1980
ORF Size (bp)
1980 bp
Protein Name (eCommerce)
Protein phosphatase Slingshot homolog 3
RefSeq ID
NM_017857
RefSeq Synonyms
NM_017857, BC007709, BC004176,
Research Areas
Axonogenesis,Cytoskeleton,Kinase/Phosphatase,Neurobiology,Phosphatase
Research Areas (Faceted)
cell_biology,developmental_biology,neurobiology,signal_transduction
Species
human
Target Sentence
SSH3, also known as slingshot-3, may function as a phosphatase that activates the actin severing protein, ADF/cofilin to indfluence actin dynamics. There are three members of the slingshot family, SSH1, SSH2, and SSH3.
UniGene ID
Hs.29173
UniProt ID (eCommerce)
Q8TE77

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.