human SRD5A3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SRD5A3.
shADV-224318
Ad-h-SRD5A3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SRD5A3 (steroid 5 alpha-reductase 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CDG1P; CDG1Q; KRIZI; SRD5A2L; SRD5A2L1
Description (Vector)
SRD5A3 belongs to the steroid 5-alpha reductase family, and polyprenol reductase subfamily. It is involved in the production of androgen 5-alpha-dihydrotestosterone (DHT) from testosterone, and maintenance of the androgen-androgen receptor activation pathway. This protein is also necessary for the conversion of polyprenol into dolichol, which is required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-linked glycosylation of proteins. Mutations in this gene are associated with congenital disorder of glycosylation type Iq.
Gene ID
79644
Gene Name (Vector)
steroid 5 alpha-reductase 3
Gene Symbol
SRD5A3
HGNC ID
HGNC:25812
ORF Size (aa)
957
RefSeq ID
NM_024592
RefSeq Synonyms
NM_024592, BC002480,
Species
human
UniGene ID
Hs.39311
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.