human SPINT2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human SPINT2.
shADV-224201
Ad-h-SPINT2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human SPINT2 (serine peptidase inhibitor, Kunitz type 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DIAR3; HAI-2; HAI2; Kop; PB
Description (Vector)
SPINT2 encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. SPINT2 is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
10653
Gene Name (Vector)
serine peptidase inhibitor, Kunitz type 2
Gene Symbol
SPINT2
HGNC ID
HGNC:11247
ORF Size (aa)
759
RefSeq ID
NM_021102
RefSeq Synonyms
NM_021102, NM_001166103, BC012868, BC011955, BC011951, BC007705, BC001668,
Species
human
UniGene ID
Hs.31439
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.