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human SPINLW1 shRNA silencing Adenovirus

Name 
Ad-h-SPINLW1-shRNA
Cat No 
shADV-224197
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human EPPIN.

shADV-224197
Ad-h-SPINLW1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human EPPIN (epididymal peptidase inhibitor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CT71; CT72; dJ461P17.2; SPINLW1; WAP7; WFDC7
Description (Vector)
EPPIN encodes an epididymal protease inhibitor, which contains both kunitz-type and WAP-type four-disulfide core (WFDC) protease inhibitor consensus sequences. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. EPPIN is a member of the WFDC gene family and belongs to the telomeric cluster. The protein can inhibit human sperm motility, and polymorphisms in this gene are associated with male infertility. Read-through transcription also exists between this gene and the downstream WFDC6 (WAP four-disulfide core domain 6) gene.
Gene ID
57119
Gene Name (Vector)
epididymal peptidase inhibitor
Gene Symbol
EPPIN
HGNC ID
HGNC:15932
ORF Size (aa)
402
RefSeq ID
NM_020398
RefSeq Synonyms
NM_020398, NM_001302861, BC053369, BC044829,
Species
human
UniGene ID
Hs.121084

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.